Rafael van der Vaart's speculative long shot just before halftime sent Tottenham Hotspur into the FA Cup fifth round with a fortunate 1-0 win at Watford on Friday.
Rooney, the all-time leading goalscorer for club and country, has started eight Premier League games this season and has not played since Feb. 1.
Manchester City's spending of more than 180 million pounds ($223.58 million) was the second-biggest outlay ever worldwide by a club in the January transfer window.
Ronaldo's behaviour on Wednesday drew criticism, with former United goalkeeper Peter Schmeichel saying the 37-year-old has become a distraction at Old Trafford.
Steven Gerrard scored two penalties as Liverpool went back to the top of the Premier League with a 2-1 win at West Ham United to complete a Merseyside win-double over London clubs on Sunday.
Phil Jagielka's stoppage-time thunderbolt earned Everton an unlikely 1-1 draw in the 223rd Merseyside derby on Saturday after Steven Gerrard's free kick appeared to have secured Liverpool a welcome victory.
Frank Lampard underlined his value to Chelsea with a well-taken double that secured a 2-1 comeback win at Everton on Sunday to move the Londoners back up to third place in the Premier League.
Liverpool moved back to the top of the Premier League with a 2-0 victory at struggling Burnley
Everton ended third-tier Oldham Athletic's giantkilling FA Cup run with a 3-1 victory in their fifth round replay on Tuesday to tee up an all Premier League quarter-final against Wigan Athletic.
Images from the English Premier League matches played on Saturday.
Everton get the chance to put a large dent in Manchester United's title hopes when they face the Premier League's injury-hit leaders at Goodison Park on Saturday.
On-loan Bolton Wanderers striker Daniel Sturridge scored his third goal in three games to wrap up a 2-0 victory over Everton in the Premier League on Sunday.
Kane began the night level on 19 goals with Liverpool's Mohamed Salah in the race for the Golden Boot.
Manchester City went top of the Premier League, at least until Manchester United play at Stoke City later on Saturday, when they beat Everton 2-0 at the Etihad Stadium with goals from second-half substitutes Mario Balotelli and James Milner.
Ruthless Arsenal threw down the gauntlet in the Premier League title race with a 5-0 thrashing of London rivals Chelsea to roar three points clear at the top of the table on Tuesday.
New Everton boss Sean Dyche's reign began with a shock 1-0 victory over English Premier League leaders Arsenal.
Manchester City and Arsenal closed in on Premier League leaders Liverpool with contrasting victories on Saturday as Manchester United's bubble was burst by Fulham.
Holders Manchester City beat Chelsea 1-0 with a late Bernardo Silva goal on Saturday to reach the FA Cup final after an absorbing end-to-end Wembley semi-final left the exhausted winners still chasing a domestic double.
Champions Manchester City have won their last 10 home league matches scoring a total of 36 goals.
A summary of Saturday's matches in the English Premier League.
Arsenal claimed their first Premier League win at Everton for six years as Leandro Trossard's second-half strike proved enough to secure the points at Goodison Park on Sunday.
The England striker's transfer value soared to 50 million pounds following his Euro 2004 performances.
Manchester United have enough in their armoury to cope with the loss of suspended striker Wayne Rooney, Everton manager Roberto Martinez warned his players on Friday ahead of this weekend's Premier League clash at Old Trafford.
A stoppage-time goal from Martin de Roon earned Middlesbrough an unlikely 1-1 draw at Premier League leaders Manchester City on Saturday.
A round-up of the action in the English Premier League on Monday.
Tottenham Hotspur continued their Premier League title push with a 2-0 win over Everton on Wednesday to put them level on points with second-placed champions Manchester United and three behind leaders Manchester City.
Everton scored twice in stoppage time to snatch an unlikely 3-3 home Premier League draw with Manchester United on Saturday in a game that Wayne Rooney missed to spare him from potential crowd abuse.
A summary of Saturday's action in the English Premier League.
The battle for Champions League qualification continues with fourth-placed Aston Villa away to Luton Town on Saturday and Tottenham Hotspur, who are five points behind with a game in hand, hosting Crystal Palace.
IMAGES from the Premier League matches played on Saturday.
Chelsea found no chink in Everton's defensive armour as the Premier League champions were held to a frustrating 0-0 draw at Goodison Park on Saturday.
News of all that's transpired on and off the football field.
Louis van Gaal accused his Manchester United players of being out-fought in a 3-0 defeat at Everton.
Manchester City moved four points clear of Arsenal atop the Premier League table with an 11th consecutive victory.
Norwich had their game at West Ham United postponed due to COVID-19 cases, injuries and illness reported among players and staff, while Leicester had matches against Tottenham Hotspur and Everton postponed due to coronavirus cases among their players.
IMAGES from the Premier League matches played on Saturday.
Images from Saturday's action in the Premier League.
Liverpool kicked off the new year three points clear atop the English Premier League standings with a 4-2 victory over Newcastle United.
Gerrard's side turned their fortunes around at the expense of the visitors under Lampard
An inspired Matteo Darmian scored his first goal for Manchester United and set up another as Louis van Gaal's side kept alive their hopes of a top-four finish with a 2-0 home win over Crystal Palace on Wednesday.